tert-butyl 2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}acetate cy3 NCCOCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%

NCCOCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

dCeMM2 (Compound 2) is a glue degrader

248 SMILES NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

284 SMILES OC(=O)CNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

378 SMILES C[C@H](NC1=CC=C2C3=NC(=CN3CCOC2=C1)N1[C@@H](COC1=O)C(F)F)C(N)=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

tert-butyl 2-{4-[2-(2-aminoethoxy)ethyl]piperazin-1-yl}acetate cy3 NCCOCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%Nitrogen Heterocycle Based Linker (NHBL). Binfunctional amine carboxylic acid linker. Product Name tert butyl 2 {4 [2 (2 aminoethoxy)ethyl]piperazin 1 yl}acetate Synonyms CAS Number 1181972 47 3 Related CAS Molecular Formula C14H29N3O3 Molecular Weight 287. 404 SMILES CC(C)(C)OC(=O)CN1CCN(CCOCCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory