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492 SMILES BrCCOCCOCCOCCOCCOCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
505 Purity (HPLC) >= 95% Solubility DMSO
SulfoCy3(Sulfo-Cyanine3
BC-Nor is a CLIP-tag substrate containing norbornene moiety for click chemistry applications
Product Name Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C63H82FN7O18 Molecular Weight 1244
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4)-Exatecan Fmoc 492 SMILES BrCCOCCOCCOCCOCCOCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
