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Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE cyclopropene Identification of a Novel Linker

SKU 42339149758
4.2
EUR495.00 EUR519.00

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Description

Identification of a Novel Linker Enabling the Bioconjugation of a Cyclic Dinucleotide for the STING Antibody-Drug Conjugate TAK-500

CA-Alexa Fluor 488 is a HaloTag fluorescent ligand and can be used to label cell surface proteins(494Ex/517Em)

the diminishing M2 character and emerging M1 markers could be simultaneously monitored in real time through the multicolor changes during macrophage reprogramming

Product Name Lenalidomide-CO-PEG1-C2-amine HCl Synonyms Lenalidomide-4'-CO-PEG1-C2-amine HCl CAS Number n/a Related CAS Molecular Formula C18H23ClN4O5 Molecular Weight 410

Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C91H149N11O28 Molecular Weight 1845

Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE cyclopropene Identification of a Novel LinkerSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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