Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Size:100mg 394 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C1C=CC=C2NCC1=CC2=CC=CC=C2O1 Purity (HPLC)

394 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C1C=CC=C2NCC1=CC2=CC=CC=C2O1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Product Name Phthalimidinoglutarimide-5'-C3-amine HCl Synonyms CAS Number n/a Related CAS 2589697-97-0 (free base) Molecular Formula C16H20ClN3O3 Molecular Weight 337

381 SMILES OC(=O)CCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

3-triazole linkages

DMF Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Size:100mg 394 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C1C=CC=C2NCC1=CC2=CC=CC=C2O1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility.