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Product Name Thalidomide-C5-Br Synonyms Thalidomide-4'-C5-Br CAS Number 2411022-24-5 Related CAS Molecular Formula C18H19BrN2O4 Molecular Weight 407
Product Name Lenalidomide-CO-C6-Br Synonyms Lenalidomide-4'-CO-C6-Br CAS Number n/a Related CAS Molecular Formula C20H24BrN3O4 Molecular Weight 450
Contains cereblon ligand Thalidomid and 5'-substituted piperazine group
specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1
68 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
HQ461 deuterium-labeled-ketone Product Name Thalidomide-C5-Br Synonyms Thalidomide-4'-C5-BrHQ461 is a molecular glue that promotes CDK12 DDB1 interaction to trigger cyclin K degradation. HQ461 mediated degradation of cyclin K impairs CDK12 function, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death. Product Name HQ461 Synonyms CAS Number 1226443 41 9 Related CAS Molecular Formula C15H15N5OS2 Molecular Weight 345. 44 SMILES CC1=CN=C(NC(=O)CC2=CSC(NC3=NC(C)=CC=C3)=N2)S1 Purity
