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Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE DNA 42 SMILES Cl

SKU 99660184151
4.8
USD495.00 USD527.00

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Description

42 SMILES Cl

Fitzgibbons

62 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

84 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name BC-Cp Synonyms CLIP-Cp

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE DNA 42 SMILES ClSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is

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